C&O Canal 100

The C&O Canal 100 is a 100-mile ultramarathon held in Knoxville, Maryland, along the scenic C&O Canal towpath near the Potomac River and Appalachian Mountains. The course features one approximately 40-mile loop followed by two 30-mile loops, starting and finishing at Camp Manidokan. Runners enjoy temperate spring weather, low elevation, and smooth terrain, making it suitable for both first-time 100-milers and experienced ultrarunners.

The race includes about seven aid stations per loop, spaced 3 to nearly 7 miles apart, offering excellent volunteer support and well-stocked supplies. This fast, friendly event is also a qualifier for the Western States Endurance Run. Visit the organization's website for the most recent information.