C&O Canal 100

The C&O Canal 100 is a 100-mile ultramarathon held in Knoxville, Maryland, along the scenic C&O Canal towpath near the Potomac River and Appalachian Mountains. The course features one approximately 40-mile loop followed by two 30-mile loops, starting and finishing at Camp Manidokan. Runners enjoy a fast, friendly route with low elevation and smooth terrain, ideal for first-time 100-milers and veterans seeking personal bests.

The race offers about seven aid stations per loop, spaced 3 to nearly 7 miles apart, providing excellent support with well-stocked supplies and enthusiastic volunteers. The event is known for its beautiful riverside scenery and temperate spring weather. Visit the organization's website for the most recent information.